Organ-system phenotypic subscores (renal, hepatic, immune, hematologic) from an existing panel — telehealth / national.

A CBC + comprehensive metabolic panel already sitting in a person's portal carries more than one whole-body PhenoAge number -- it carries independently validated, system-specific risk signals nobody is reading together: kidney function (eGFR), liver-fibrosis risk (FIB-4), immune/inflammatory tone (neutrophil:lymphocyte ratio), and a hematologic aging marker (RDW). Levine's 2013 senescence-modeling work established that a routine panel carries this system-level information; this packet reads FOUR of those signals off the same panel a person already holds, each its own real published formula, never a single invented composite. Where the panel cannot honestly support a subscore (a general 'metabolic' or cardiovascular composite needs lipids/HbA1c a CMP does not carry), it is skipped and said so, not faked.

Where

Telehealth / national (compute over an existing panel) · Open the map

Pay

$140 proposed

This packet is not funded yet, so this figure is a proposed price and not money waiting in escrow. If a buyer funds it, approved proof settles that price onchain. If nobody funds it, approved proof earns provable credit toward the work instead of cash — recorded, and readable any time at vealth.net/labor/credit/(your wallet). You see which before you claim, never after.

Proof

the panel inputs used per subscore (creatinine + age + sex for renal; AST + ALT + platelets + age for hepatic; neutrophil % + lymphocyte % + WBC [+ CRP] for immune; RDW + MCV for hematologic) + each computed subscore + its published reference band, framed as research-grade risk-screening signals, never a diagnosis

This is exactly what gets it approved. Nothing settles without it.

Level

intermediate

Open until

2027-08-30

Posted by

0x034F…6c89

The creator wallet. Its signature is what approves proof and settles the wage.

How this work is done

A documented method, so this packet comes out the same whoever does it.

Bring

• a recent (ideally <=6 month) accredited-lab CBC with differential + comprehensive metabolic panel, with a copy/printout for the record
• the person's chronological age and sex assigned at birth (required for the eGFR and FIB-4 formulas)
• an optional hs-CRP result, if already drawn, for immune-subscore context (not required)
• the compute tool (`npm run health:organ-subscores`)
• a secure note for raw panel values, the four computed subscores, their published reference bands, and any clinician referral

Steps

1. 1. Obtain (or use an existing) accredited-lab CBC with differential + comprehensive metabolic panel; record age, sex, creatinine, AST, ALT, platelet count, neutrophil %, lymphocyte %, WBC, RDW, and MCV, each with units and the draw date. Record hs-CRP too if it was already drawn (optional, never ordered new for this packet alone).
2. 2. Confirm units match the tool's expected US clinical units (creatinine mg/dL, AST/ALT U/L, platelets 10^3/uL, WBC 10^3/uL, RDW %, MCV fL, hs-CRP mg/L).
3. 3. Run `npm run health:organ-subscores -- --age .. --sex .. --creatinine .. --ast .. --alt .. --platelets .. --neutrophil-pct .. --lymphocyte-pct .. --wbc .. --rdw .. --mcv .. [--crp ..]` to compute the four subscores.
4. 4. For any required input group that is missing or implausible (e.g., no platelet count on file), leave that specific subscore blank rather than estimate or impute it, and record the reason.
5. 5. Record each computed subscore with its own published reference band and citation, framed as a research-grade risk-screening signal and a personal trend across repeated panels, never a diagnosis, and never fused into one composite number.
6. 6. Route any single flagged subscore (elevated / indeterminate / high / borderline per its own published band) to the appropriate licensed clinician, sign the record, and set a retest cadence.

What counts as done

• All available panel values used, from an accredited lab, with units and draw date (creatinine, AST, ALT, platelet count, neutrophil %, lymphocyte %, WBC, RDW, MCV; hs-CRP optional)
• Each computable subscore (renal eGFR + KDIGO stage, hepatic FIB-4 + band, immune NLR + optional CRP context, hematologic RDW + MCV class) recorded via `npm run health:organ-subscores`, with any subscore missing required inputs explicitly marked skipped, never estimated
• Each subscore reported with its own published reference band and citation, explicitly framed as a research-grade risk-screening trend, never a diagnosis or a single fabricated composite
• Any flagged subscore routed to a licensed clinician, noted in the record

Proof is measured against these, not judged by taste.