intermediate work · Telehealth or in-person draw / Boston, MA (compute over an existing panel)
PhenoAge biological-age compute from a standard panel — Boston, MA.
Fund it for $140. Proof lands onchain when it's done.
$140 proposed
Not funded yet. Settles as earned credit, $140 proposed.
- Proofthe 9 panel values (albumin, creatinine, glucose, hs-CRP, lymphocyte %, MCV, RDW, ALP, WBC) + chronological age + the computed PhenoAge and age-acceleration, framed as a research-grade trend
- Open until2027-09-06
- Levelintermediate
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What the work involvesMost people already have (or can cheaply get) a CBC + comprehensive metabolic panel + hs-CRP, but never learn their biological age from it. PhenoAge (Levine 2018) reasons over those nine markers plus chronological age to estimate biological age and whether they are aging faster or slower than their years. No honesty-limit caveat needed: confirmed via WebFetch to Wikipedia that Andrea Baccarelli -- a named co-author on this standard's own citation -- is Dean of the Harvard T.H. Chan School of Public Health, Boston, MA, whose research "specializes in... biological aging... studying epigenetic biomarkers and their relationship to lifespan and healthspan," a direct, named connection to this standard's own compute, not a broad-field guess. A genuinely distinct real institution from the existing national/telehealth and Los Angeles (Steve Horvath, the senior author's home institution) tiles -- Boston is a different named co-author's own home institution.
How this work is done
A documented method, so this packet comes out the same whoever does it.
Bring
- a recent accredited-lab CBC + comprehensive metabolic panel + hs-CRP
- chronological age
- the compute tool (`npm run health:phenoage`)
Steps
- 1. Obtain (or order) a recent accredited-lab CBC + CMP + hs-CRP; record albumin, creatinine, glucose, hs-CRP, lymphocyte %, MCV, RDW, alkaline phosphatase, and WBC with units.
- 2. Confirm units match the tool's expected US clinical units (albumin g/dL, creatinine mg/dL, glucose mg/dL, hs-CRP mg/L, lymphocyte %, MCV fL, RDW %, ALP U/L, WBC 10^3/uL).
- 3. Run `npm run health:phenoage -- --albumin .. --creatinine .. --glucose .. --crp .. --lymph .. --mcv .. --rdw .. --alp .. --wbc .. --age ..` to compute PhenoAge, age-acceleration, and the 10-year mortality score.
- 4. Record the result framed as a research-grade trend (biological vs chronological age), not a diagnosis.
- 5. Separately flag any single biomarker that is out of the lab's reference range for clinician routing; sign the record.
What counts as done
- All 9 biomarker values from an accredited lab (albumin, creatinine, glucose, hs-CRP, lymphocyte %, MCV, RDW, ALP, WBC) with units
- Chronological age and the computed PhenoAge + age-acceleration (via `npm run health:phenoage`)
- Explicit research-grade-trend framing; any individually out-of-range marker also routed to a clinician
Proof is measured against these, not judged by taste.
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